Whipple Disease of the Central Nervous System
نویسندگان
چکیده
منابع مشابه
Whipple disease of the central nervous system.
In 1907, George H. Whipple reported the clinical manifestations and autopsy findings for a patient with the disease that now bears his name [1]. Nearly all of the cardinal clinical manifestations of this disorder—including arthralgias, abdominal pain, fever, diarrhea, malabsorption, weight loss, and cough—were evident in this first patient reported. On the basis of observations of fat and fatty...
متن کاملCentral Nervous System Involvement in Whipple Disease
Whipple disease (WD) is a rare multisystemic infection with a protean clinical presentation. The central nervous system (CNS) is involved in 3 situations: CNS involvement in classic WD, CNS relapse in previously treated WD, and isolated CNS infection. We retrospectively analyzed clinical features, diagnostic workup, brain imaging, cerebrospinal fluid (CSF) study, treatment, and follow-up data i...
متن کاملWhipple disease confined to the central nervous system in childhood.
In a case of pediatric Whipple disease confined to the central nervous system, white matter lesions initially appeared as areas of very low signal intensity on T1-weighted MR images and as areas of hyperintensity on proton density-weighted and T2-weighted images, and showed slight peripheral enhancement on delayed contrast-enhanced T1-weighted images. On MR studies obtained 3 and 6 months after...
متن کاملCerebellar ataxia and central nervous system whipple disease.
BACKGROUND Whipple disease (WD) is an infectious disease, which may affect the central nervous system. Central nervous system symptoms are eventually present in as many as 43% of the cases. To our knowledge, cerebellar ataxia in WD has never been formally studied in any large series. OBJECTIVE To determine the prevalence of cerebellar ataxia in central nervous system WD. RESULTS Between Jan...
متن کاملADENOSINE IN THE CENTRAL NERVOUS SYSTEM
Besides being a metabolite of nucleotides like ATP, adenosine is a mediator of neuronal function in the central nervous system. Its actions are mediated by at least three extracellular receptors. In this review different aspects of adenosine such as biosynthesis, release, inactivation and its receptors are discussed. It also covers pre- and postsynaptic effects as well as postreceptor mecha...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: The Journal of Infectious Diseases
سال: 2003
ISSN: 0022-1899,1537-6613
DOI: 10.1086/378075